早期接触“永远的化学品”会扰乱小鼠的肠内微生物,有可能导致肥胖和2型糖尿病。 Early-life exposure to 'forever chemicals' disrupts gut microbiome in mice, potentially contributing to obesity and type 2 diabetes.
由宾夕法尼亚州州立研究人员领导的一项新研究表明,在环境中早期接触2,3,7,8-四氯二苯并呋喃(TCDF)等“永远的化学品”,永久性地扰乱小鼠的肠内微生物,导致后代出现肥胖和2型糖尿病等代谢疾病。 A new study led by Penn State researchers reveals that early-life exposure to 'forever chemicals' in the environment, such as 2,3,7,8-tetrachlorodibenzofuran (TCDF), permanently disrupts the gut microbiome in mice, leading to the development of metabolic diseases like obesity and type 2 diabetes in later life. 研究表明,人类在幼儿期接触这些化学品可能助长最近代谢紊乱的流行。 The research suggests that human exposure to these chemicals during early childhood may be contributing to the recent epidemic of metabolic disorders. 研究发现,即使在化学物质从体内排出后,早期接触TCDF可能会导致肠道微生物组功能和健康结果的障碍. The study discovered that early-life TCDF exposure may cause disturbances in gut microbiome function and health outcomes later in life, even after the chemical has been eliminated from the body. 研究人员建议,未来的研究可以通过补充前生和前生生物,使一个人的微生物恢复到其最佳状态,这将有助于减轻接触这些化学品对健康的长期影响。 The researchers propose that future research could lead to restoring a person's microbiome to its optimal state through supplementation with pre- and probiotics, which could help mitigate the long-term health effects of exposure to these chemicals.