由维利亚博士领导的威斯塔研究所的研究人员发现了胶质母细胞瘤如何通过葡萄糖驱动的组蛋白乳酸化来抑制免疫系统。 Wistar Institute researchers, led by Dr. Veglia, discovered how glioblastoma suppresses immune system via glucose-driven histone lactylation.
由菲利波·维利亚博士领导的威斯塔研究所研究人员发现了一种致命脑癌——胶质母细胞瘤抑制免疫系统的关键机制。 Wistar Institute researchers, led by Dr. Filippo Veglia, discovered a key mechanism by which glioblastoma, a deadly brain cancer, suppresses the immune system. 他们的研究成果发表在《免疫》杂志上,揭示了葡萄糖驱动的组蛋白乳化如何促进胶质母细胞瘤中单核细胞衍生的巨噬细胞的免疫抑制活性。 Their findings, published in Immunity journal, reveal how glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma. Veglia 博士认为,了解这些机制有助于开发针对这种癌症的有效治疗方法。 Dr. Veglia believes that understanding these mechanisms could help develop effective treatments against this cancer.