研究者发现脑癌 重新编程免疫细胞 支持肿瘤生长 可能帮助新的治疗 Researchers discover brain cancers reprogram immune cells to support tumor growth, potentially aiding new treatments.

威斯塔尔研究所的研究人员发现 激进的脑癌 可以重新编程免疫细胞 叫做神经营养素 来支持肿瘤的生长 而不是对抗肿瘤的生长 Researchers at The Wistar Institute found that aggressive brain cancers can reprogram immune cells called neutrophils to support tumor growth instead of fighting it. 在瘤中氧气较低的区域中,中性粒细胞增加葡萄糖的使用,产生激活ARG1基因的乳酸,从而抑制免疫反应. In low-oxygen areas of tumors, neutrophils increase their glucose use, producing lactate that activates a gene called ARG1, which suppresses the immune response. 这种发现可能导致新的治疗方法,以提高免疫疗法对脑癌的防治效果。 This discovery could lead to new treatments to enhance immunotherapy effectiveness against brain cancers.