科学家发现DNA序列的过度重复导致亨廷顿病的脑细胞死亡 Scientists find that excessive repeats of a DNA sequence cause brain cell death in Huntington's disease.

科学家发现了有关亨廷顿病的关键细节 一种致命的神经疾病 Scientists have uncovered a key detail about Huntington's disease, a fatal neurological disorder. 他们发现,当特定DNA序列(CAG)重复40次或40次以上对疾病负责的基因,这些重复会随着时间推移而扩大。 They found that when a specific DNA sequence, CAG, repeats 40 or more times in the gene responsible for the disease, these repeats expand over time. 一旦重复达到约150, 某些脑细胞开始死亡, 导致亨廷顿的出现。 Once the repeats reach about 150, certain brain cells begin to die, leading to the onset of Huntington's. 这种发现可能导致采用新方法来推迟或预防这一疾病,这一疾病影响到大约41 000名美国人,目前没有治疗方法。 This discovery could lead to new methods to delay or prevent the disease, which affects around 41,000 Americans and currently has no cure.