研究人员开发了SPLICER,这是一个基因编辑工具,可以减少阿尔茨海默氏氏病小鼠中的氨基类细胞斑块。 Researchers developed SPLICER, a gene editing tool that reduces amyloid-beta plaque in Alzheimer's mice.

伊利诺伊大学Urbana-Chempaign的研究人员开发了一个新的基因编辑工具,称为SPLICER, 成功地减少了在患有阿尔茨海默氏病的小鼠体内形成氨基甲状腺-贝塔红斑前体的情况。 Researchers at the University of Illinois Urbana-Champaign have developed a new gene editing tool called SPLICER that successfully reduced the formation of amyloid-beta plaque precursors in mice with Alzheimer's disease. SPLICER使用exon skipping,这种方法可以帮助治疗有毒蛋白引起的疾病,如肌肉萎缩和亨廷顿病。 SPLICER uses exon skipping, a method that could help treat diseases caused by toxic proteins, like muscular dystrophy and Huntington's disease. 在测试中,SPLICER将目标基因部分减少了25%,没有非目标效果,显示出治疗各种遗传条件的前景。 In tests, SPLICER reduced targeted gene segments by 25% with no off-target effects, showing promise for treating various genetic conditions.