人类本能的T细胞发育与小鼠不同,影响免疫能力,需要在免疫疗法发育中加以考虑。 Human innate-like T cell development differs from mice, affecting immune capabilities and requiring consideration in immunotherapy development.
冷泉港实验室和科罗拉多安舒茨大学的一项研究发现,人类内原型T细胞的发育与小鼠不同,影响它们的免疫能力。 A study by Cold Spring Harbor Laboratory and the University of Colorado Anschutz found that innate-like T cells in humans develop differently than in mice, affecting their immune capabilities. 在人类中,这些细胞在早期生活中功能较弱,但在成年时成熟。 In humans, these cells are less functional in early life but mature in adulthood. 这项研究强调,在发展免疫疗法时必须考虑到这些差异,因为大多数临床前试验都使用鼠标模型。 This research emphasizes the need to consider these differences when developing immunotherapies, as most preclinical tests use mouse models. 调查结果旨在加强癌症治疗战略。 The findings aim to enhance cancer treatment strategies.