瑞典研究人员发现了一种对抗多重耐药细菌的新型抗生素,以 LpxH 为目标,治愈小鼠的血液感染。 Swedish researchers found a new antibiotic class that combats multi-drug resistant bacteria, targeting LpxH and curing bloodstream infections in mice.
据《美国国家科学院院刊》报道,乌普萨拉大学的瑞典研究人员发现了一类新型抗生素,可以有效对抗多重耐药细菌。 Swedish researchers at Uppsala University have discovered a new class of antibiotics that effectively combat multi-drug resistant bacteria, as reported in PNAS. 这种新型抗生素以 LpxH 为靶点,LpxH 是一种参与革兰氏阴性细菌脂多糖合成的蛋白质。 This novel antibiotic class targets LpxH, a protein involved in the synthesis of lipopolysaccharide in Gram-negative bacteria. 研究人员发现,这些新抗生素可以治愈小鼠的血液感染,可能为日益严重的抗生素耐药性问题提供解决方案。 The researchers found that these new antibiotics can cure bloodstream infections in mice, potentially providing a solution to the growing problem of antibiotic resistance.