NIH研究发现,APOL1基因变异与西非肾病风险增加有关。 NIH study finds APOL1 gene variant linked to increased kidney disease risk in West Africans.

最近的一项NIH研究查明了西非肾病的一个重要遗传风险因素,表明加纳和尼日利亚近三分之一的人带有APOL1基因变异。 A recent NIH study identified a significant genetic risk factor for kidney disease in West Africans, revealing that nearly one-third of individuals in Ghana and Nigeria carry the APOL1 gene variant. 这一变式增加了慢性肾病的风险,其中一种变式将风险增加了18%,两种变式增加了25%。 This variant increases the risk of chronic kidney disease, with one variant raising the risk by 18% and two by 25%. 调查结果强调,必须研究各种人口,以提高对肾病的了解和治疗,这也会使受影响的美国人受益。 The findings underscore the importance of studying diverse populations to improve understanding and treatment of kidney diseases, which could also benefit affected Americans.