第三阶段试验表明,对脑转移进行辐射治疗的认知副作用是可以逆转的,75%的病人恢复了某种认知功能。 3 Phase III trials suggest cognitive side effects from radiation therapy for brain metastases may be reversible, with 75% of patients regaining some cognitive function.
对ASTRO年度会议上介绍的第三阶段三期临床试验的综合分析表明,对脑转移病人的辐射治疗的认知副作用可能完全可以逆转。 A pooled analysis of three Phase III clinical trials presented at the ASTRO Annual Meeting indicates that cognitive side effects from radiation therapy in patients with brain metastases may be fully reversible. 6个月恢复率为38%,一年后认知后下降为42%,与标准的全脑治疗相比,接受符合要求的辐射技术治疗的人的恢复率为38%,一年后认知后下降为42%,结果有所改善。 Recovery rates were 38% at six months and 42% at one year post-cognitive decline, with improved outcomes seen in those treated with conformal radiation techniques compared to standard whole-brain therapy. 总体而言,大约75%的病人恢复了某种认知功能。 Overall, about 75% of patients regained some cognitive function.