研究人员查明了涉及蛋白质GSDMD的主要发炎机制,这可能导致对败血症和自发炎疾病的治疗。 Researchers identify key mechanisms of inflammation involving protein GSDMD, potentially leading to treatments for sepsis and autoinflammatory diseases.

波恩大学医院和波恩大学的研究人员发现了涉及蛋白质 gasdermin D （GSDMD） 的炎症关键机制，该蛋白在细胞膜上形成孔，促进炎症反应和细胞死亡。 Researchers at the University Hospital Bonn and the University of Bonn have uncovered key mechanisms of inflammation involving the protein gasdermin D (GSDMD), which forms pores in cell membranes, facilitating inflammatory responses and cell death. 他们利用纳米体,发现这些碎片会抑制孔隙形成,可能导致对败血症和自炎疾病等疾病的治疗。 Utilizing nanobodies, they found these fragments can inhibit pore formation, potentially leading to treatments for conditions like sepsis and autoinflammatory diseases. 他们的发现在“自然通讯”中详述。 Their findings are detailed in "Nature Communications."