研究发现男性纤维细胞的与年龄相关的变化导致了侵袭性,耐治疗的黑色素瘤. Study finds age-related changes in male fibroblasts contribute to aggressive, treatment-resistant melanoma.
约翰霍普金斯金梅尔癌症中心的一项研究显示, 纤维细胞的年龄相关变化导致男性患有侵袭性,耐治疗的黑色素瘤, 风险高于女性. A study from Johns Hopkins Kimmel Cancer Center reveals that age-related changes in fibroblasts contribute to aggressive, treatment-resistant melanoma in men, who are at higher risk than women. 男性纤维细胞的衰老速度更快, 产生更多的活性氧物种, 增加癌症的严重程度. Male fibroblasts age faster and produce more reactive oxygen species, increasing cancer severity. 研究强调,需要了解性别差异和细胞变化,以针对黑瘤制定有针对性的治疗方法。 The research highlights the need to understand sex differences and cellular changes for developing tailored therapies targeting melanoma.