研究发现,在严重的低背痛方面,Modic变化与腰脊椎微生物多样性之间存在联系。 Study finds link between Modic changes and lumbar spine microbial diversity in relation to severe low back pain.
骨关节外科杂志的一项研究发现,在经历腰椎融合的患者中,Modic变化与腰椎软骨末端板中的微生物多样性和代谢物差异有关. A study in The Journal of Bone & Joint Surgery found that Modic changes in patients undergoing lumbar spinal fusion are linked to differences in microbial diversity and metabolites in lumbar cartilaginous endplates. 在 MRI 上检测到的 Modic 变化可能导致严重的腰痛，并与腰椎间盘突出症有关。 Modic changes, detected on MRI, may lead to severe low back pain and are related to lumbar disc herniation. 这项研究表明,微生物体的变化会破坏LCEP内不饱和脂肪酸新陈代谢,有可能影响Modic变化的开始和进展。 This research suggests that changes in microbiota disrupt unsaturated fatty acid metabolism within LCEPs, potentially influencing the onset and progression of Modic changes. 研究结果可能会为与Modic变化相关的疾病提供新的诊断和治疗策略. The study's findings may lead to new diagnostic and therapeutic strategies for conditions related to Modic changes.