马克斯德尔布吕克中心的研究人员开发了高分辨率空间转录组学平台 Open-ST,从患者组织样本创建 3D 分子图,用于药物靶点发现。 Researchers at Max Delbrück Center developed high-resolution spatial transcriptomics platform Open-ST, creating 3D molecular maps from patient tissue samples for drug target discovery.
马克斯德尔布吕克中心的研究人员开发了一个开源平台 Open-ST,该平台可以根据患者组织样本创建具有亚细胞精度的 3D 分子图。 Researchers at the Max Delbrück Center have developed an open-source platform, Open-ST, that creates 3D molecular maps from patient tissue samples with subcellular precision. 这种高分辨率空间转录组学平台使科学家能够重建组织内细胞的基因表达,有可能帮助研究人员发现药物靶点和新疗法。 This high-resolution spatial transcriptomics platform allows scientists to reconstruct gene expression in cells within a tissue, potentially helping researchers discover drug targets and new therapies. 该项研究发表在《细胞》杂志上。 The study was published in the journal "Cell."