艾德克斯治疗公司的实验GABAB调节剂减少了灵长类动物咳,比巴科芬更好地耐受. Addex Therapeutics' experimental GABAB modulator reduces cough in primates with improved tolerability over baclofen.

据Addex Therapeutics报告,其实验性GABAB正异质调节剂成功降低了非人类灵长类动物的咳频率,并具有良好的安全概况. Addex Therapeutics reports that its experimental GABAB positive allosteric modulator successfully reduced cough frequency in non-human primates with a favorable safety profile. 药物显示抗咳效果与巴克洛芬相似,它用于非标签的咳但有副作用,同时提供更好的耐受性. The drug showed anti-tussive effects comparable to baclofen, which is used off-label for cough but has side effects, while offering better tolerability. 候选药物可口服,设计用于每天一次剂量. The candidate is orally available and designed for once-daily dosing.