一个新的蛋白质图谱揭示了6种神经退行性疾病中共享和独特的分子模式, 识别出80%以前未连接的蛋白质.
A new protein atlas reveals shared and unique molecular patterns across six neurodegenerative diseases, identifying 80% of previously unlinked proteins.
一个新的蛋白质图谱,PanNDA,利用2,279人的数据绘制了六种主要神经退行性疾病的共同和独特分子模式.
A new protein atlas, PanNDA, maps shared and unique molecular patterns across six major neurodegenerative diseases using data from 2,279 individuals.
这项由圣犹大儿童研究医院和合作者开发的公开资源揭示了常见蛋白质通路和潜在疾病亚型, 确定80%以前与神经退行相关不联的蛋白质.
Developed by St. Jude Children’s Research Hospital and collaborators, the publicly available resource reveals common protein pathways and potential disease subtypes, identifying 80% of proteins not previously linked to neurodegeneration.
这项研究发表在"细胞"杂志上, 突出了参与疾病进展的关键蛋白质和网络, 为诊断和治疗提供新的点.
The study, published in Cell, highlights key proteins and networks involved in disease progression, offering new targets for diagnostics and therapies.