中国科学家制造出一种基于红细胞的囊, 可以将健康的线粒体输入细胞中,改善能量生产并扭转疾病模型中的症状.
Chinese scientists created a red blood cell-based capsule that delivers healthy mitochondria into cells, improving energy production and reversing symptoms in disease models.
中国研究人员开发了一种新的线粒体囊疗法, 采用红细胞膜将健康的线粒體送入细胞中, 从5%以下提高到80%左右.
Chinese researchers have developed a new mitochondrial capsule therapy using red blood cell membranes to deliver healthy mitochondria into cells, boosting delivery efficiency from under 5% to about 80%.
这种方法可以帮助线粒体逃避细胞防御,融入细胞并恢复能量生产.
The method helps mitochondria evade cellular defenses, integrate into cells, and restore energy production.
在实验室和动物研究中,它减少了缺陷的线粒体,改善细胞功能,并逆转帕金森病模型中的症状,利氏综合征和线粒體DNA删除综合症,防止神经元损失和延长寿命.
In lab and animal studies, it reduced faulty mitochondria, improved cellular function, and reversed symptoms in models of Parkinson’s disease, Leigh syndrome, and mitochondrial DNA deletion syndrome, preventing neuron loss and extending lifespan.
这项研究结果发表在"细胞"杂志上, 表明对线粒体和神经退行性疾病的新疗法有潜力.
The findings, published in Cell, suggest a potential new treatment for mitochondrial and neurodegenerative diseases.