瑞典的一项研究发现, 一次抗生素治疗可以损害肠道细菌长达8年, 这会增加长期健康风险. A Swedish study finds one antibiotic course can harm gut bacteria for up to 8 years, raising long-term health risks.

瑞典对近15000名成年人进行的一项大型研究发现,即使是一次服用某些抗生素 (尤其是克林达米辛,化诺隆和流沙西林) 的疗程也能改变肠道微生物群长达八年,使微生物多样性持续减少并导致细菌组成发生变化. A large Swedish study of nearly 15,000 adults finds that even a single course of certain antibiotics—especially clindamycin, fluoroquinolones, and flucloxacillin—can alter the gut microbiome for up to eight years, with lasting reductions in microbial diversity and shifts in bacterial composition. 虽然在前两年恢复速度最快,但完全恢复很少发生,特别是重复或长时间使用. While recovery is fastest in the first two years, full restoration is rare, particularly with repeated or prolonged use. 根据国家处方记录和便测序的研究结果表明,长期健康风险包括2型糖尿病和胃肠道问题,促使人们要求更谨慎地开抗生素. The findings, based on national prescription records and fecal sequencing, suggest long-term health risks including type 2 diabetes and gastrointestinal issues, prompting calls for more cautious antibiotic prescribing.