鼻检测可以在症状出现前几年通过发现鼻细胞中的基因变化来检测阿尔茨海默病, 在早期试验中准确率为81%. A nasal swab detects Alzheimer’s years before symptoms by spotting gene changes in nose cells, with 81% accuracy in early trials.

杜克大学的一项研究发现,通过分析鼻子嗅觉层细胞中的基因活动, 鼻腔的拭片可以在症状出现前几年就能检测出阿尔茨海默病. A Duke University study finds a nasal swab may detect Alzheimer’s disease years before symptoms appear by analyzing gene activity in cells from the nose’s olfactory lining. 在一项22名参与者的小试验中,该测试以81%的准确度确定了与阿尔茨海默氏症相关的模式,包括无症状且具有生物标志物的个体. In a small trial of 22 participants, the test identified Alzheimer’s-related patterns with 81% accuracy, including in asymptomatic individuals with biological markers. 通过使用刷子收集鼻细胞后的非侵入性方法, 可以提前诊断和治疗, 可能改善结果. The non-invasive method, which uses a brush to collect cells after numbing the nose, could enable earlier diagnosis and treatment, potentially improving outcomes. 研究人员认为鼻细胞反映了早期的大脑变化, 提供了一个有希望的窗口到疾病发. Researchers believe the nasal cells reflect early brain changes, offering a promising window into the disease’s onset. 虽然该方法还不是诊断工具,但如果更大规模的试验证实其可靠性,则有可能广泛使用. While not yet a diagnostic tool, the approach holds potential for widespread use if larger trials confirm its reliability.