印度医生利用干细胞治疗不育症,导致有子宫严重疤痕的妇女两次成功分娩。
Indian doctors used stem cells to treat infertility, leading to two successful births in women with severe uterine scarring.
新德里Sir Ganga Ram医院的医生们报告说,印度有两例成功活产,他们使用子宫骨髓衍生干细胞疗法治疗严重的Asherman综合症,这是一种因子宫疤导致不育的情况。
Doctors at Sir Ganga Ram Hospital in New Delhi have reported two successful live births in India using umbilical cord-derived stem cell therapy to treat severe Asherman’s Syndrome, a condition causing infertility due to uterine scarring.
这项实验性治疗是参与10名女性的临床试验的一部分,该试验涉及将沃顿中的中介质干细胞在宫内膜中注射在宫镜指导下,旨在在没有支架的情况下再生受损的子宫内膜组织.
The experimental treatment, part of a clinical trial involving 10 women, involved injecting mesenchymal stem cells from Wharton’s jelly into the uterine lining under hysteroscopic guidance, aiming to regenerate damaged endometrial tissue without scaffolds.
两名39岁和40岁的病人显示,腹部厚度和月经流动情况有所改善,使胚胎在35周和31周内成功冷冻转产和接生健康婴儿。
Two patients, aged 39 and 40, showed improved endometrial thickness and menstrual flow, enabling successful frozen embryo transfers and deliveries of healthy babies at 35 and 31 weeks, respectively.
其结果标志着这一无脚手架办法的第一批全球报告之一,为可能无法治愈的子宫损伤的妇女提供了潜在的生育再生选择,特别是在代孕受限的印度。
The results mark one of the first global reports of this scaffold-free approach and offer a potential fertility-restoring option for women with otherwise untreatable uterine damage, especially in India where surrogacy is restricted.
审判继续进行,有8名病人正在接受后续治疗。
The trial continues with eight patients under follow-up.