一个19岁患有罕见的免疫紊乱症的孩子 第一次被治愈 使用原始编辑, 一种新的基因疗法。 A 19-year-old with a rare immune disorder became the first cured using prime editing, a new gene therapy.

来自不列颠哥伦比亚Kelowana的19岁男子成为第一个治愈慢性颗粒性疾病的患者,这是一种罕见的遗传性免疫障碍,使用原始编辑技术,一种新的基因编辑技术。 A 19-year-old man from Kelowna, B.C., has become the first person cured of chronic granulomatous disease, a rare genetic immune disorder, using prime editing, a new gene-editing technique. 治疗由第一医学开发并在蒙特利尔临床试验中测试,纠正了病人自己细胞中的缺陷基因,然后又重新引入了这些基因,从而消除了对日常抗生素和抗风素的需求。 The treatment, developed by Prime Medicine and tested in a Montreal clinical trial, corrected the faulty gene in the patient’s own cells, which were then reintroduced, eliminating the need for daily antibiotics and antifungals. 新英格兰医学杂志报道的这一程序标志着精准医学的一个里程碑,为治疗其他罕见遗传疾病带来了希望。 The procedure, reported in the New England Journal of Medicine, marks a milestone in precision medicine and offers hope for treating other rare genetic diseases.