高纬度生活可能会通过刺激红血球的葡萄糖吸收而降低糖尿病风险,这种过程仿照了老鼠中一种有前途的新药物。 High-altitude living may lower diabetes risk by boosting red blood cells' glucose absorption, a process mimicked by a promising new drug in mice.

生活在高海拔地区的人患糖尿病的风险可能较低,一项新的研究发现,红血细胞在低氧条件下充当葡萄糖汇,吸收更多的糖,帮助向组织输送氧气。 People living at higher altitudes may have a lower risk of diabetes, with a new study finding that red blood cells act as glucose sinks in low-oxygen conditions, absorbing more sugar to help deliver oxygen to tissues. 研究人员发现,在缺氧情况下,红血细胞通过骨髓中编程的GLUT1运输器增加葡萄糖的吸收,将葡萄糖转化为2,3-DPG,以提高氧气释放。 Researchers discovered that under hypoxia, red blood cells increase glucose uptake via GLUT1 transporters programmed in the bone marrow, converting glucose into 2,3-DPG to enhance oxygen release. 这个过程降低血糖,即使没有胰岛素。 This process lowers blood sugar, even without insulin. 一种称为天花病的药物,它模仿高海拔病情,比目前一些治疗方法更有效地扭转糖尿病小鼠的高血糖,为糖尿病治疗提供了有希望的新办法。 A drug called HypoxyStat, which mimics high-altitude conditions, reversed high blood sugar in diabetic mice more effectively than some current treatments, offering a promising new approach to diabetes therapy.