新研究发现,失去Y染色体的老年男子面临心脏病、癌症和寿命较短的风险较高。 Aging men losing Y chromosomes face higher risks of heart disease, cancer, and shorter lives, new study finds.

男性自然会随着年龄而失去Y染色体,这是影响近一半老年男性的一个状况。 新的研究将Y染色体(LOY)的丧失与较高的心脏病风险、某些癌症、认知下降和寿命缩短联系起来。 Men naturally lose Y chromosomes with age, a condition affecting nearly half of older men, and new research links this mosaic loss of the Y chromosome (LOY) to higher risks of heart disease, certain cancers, cognitive decline, and shorter lifespans. 这一损失发生在血细胞和组织细胞中,可能损害细胞功能和削弱免疫力,尽管确切原因仍不清楚。 The loss, which occurs in blood and tissue cells, may impair cellular function and weaken immunity, though exact causes remain unclear. 虽然LOY日益成为老龄化的标志,但科学家正在研究它是否直接引发疾病,还是更广泛的老龄化过程的症状,潜在的未来治疗方法仍在开发之中。 While LOY is a growing marker of aging, scientists are studying whether it directly drives disease or is a symptom of broader aging processes, with potential future treatments still under development.