类固醇治疗使胶质母细胞瘤肿瘤依赖甲硫氨酸，低甲硫氨酸饮食在实验室模型中减缓肿瘤生长。 Steroid treatment makes glioblastoma tumors dependent on methionine, and low-methionine diets slowed tumor growth in lab models.

科学家发现了在血浆瘤中的代谢脆弱性,这是一种致命的脑癌,与肿瘤细胞如何处理维生素B3和甲硫磷相关联。 Scientists have discovered a metabolic vulnerability in glioblastoma, a deadly brain cancer, linked to how tumor cells process vitamin B3 and methionine. 包括英国苏格兰癌症研究所在内的5个欧洲国家机构参与的研究发现,普通类固醇治疗改变了癌症细胞新陈代谢,造成对甲硫磷的依赖。 Research involving institutions from five European countries, including the Cancer Research UK Scotland Institute, found that common steroid treatments alter cancer cell metabolism, creating a dependency on methionine. 在临床前模型中,将类固醇与低甲基苯丙胺饮食相结合,减缓肿瘤的生长速度。 In preclinical models, combining steroids with a low-methionine diet slowed tumor growth. 研究结果发表在《科学进步》上,其中建议采取饮食干预措施,这可以加强目前的治疗方法,为减缓疾病蔓延提供潜在的新战略。 The findings, published in Science Advances, suggest dietary interventions could enhance current therapies, offering a potential new strategy to slow disease progression. 专家称这项发现大有希望,但需要进行人类试验,以确认其好处。 Experts call the discovery promising but note human trials are needed to confirm benefits.