UGA科学家发现250个基因对肌肉细胞聚变至关重要,包括CHAMP1与罕见的儿童肌肉紊乱有关。 UGA scientists find 250 genes vital for muscle cell fusion, including CHAMP1 linked to rare childhood muscle disorder.

格鲁吉亚大学研究人员为人类肌肉细胞开发了第一个CRISPR筛选平台,确定了250个对子宫核聚变至关重要的基因,其中包括41个与发育肌肉紊乱有关的基因。 University of Georgia researchers have developed the first CRISPR screening platform for human muscle cells, identifying 250 genes essential for myoblast fusion, including 41 linked to developmental muscle disorders. 该研究强调CHAMP1基因在调节Myomaker方面的作用,Myomaker是肌肉细胞聚变的关键蛋白质,为罕见的童年病症提供了深刻的见解。 The study highlights the CHAMP1 gene’s role in regulating Myomaker, a protein critical for muscle cell fusion, offering insights into a rare childhood disorder. 调查结果提供了一个遗传路线图,以改善先天性肌肉状况的诊断和未来治疗。 Findings provide a genetic roadmap to improve diagnosis and future therapies for congenital muscle conditions.