由于歧视造成的慢性压力是圣路易斯研究中黑人-白人死亡率差距近一半的原因。 Chronic stress from discrimination explains nearly half of the Black-White mortality gap in a St. Louis study.

2026年在JAMA Network Open进行的一项研究发现,黑人和白人美国人之间种族死亡率差距的近一半与终身遭受歧视造成的长期压力和炎症有关。 A 2026 study in JAMA Network Open finds that nearly half of the racial mortality gap between Black and White Americans is linked to chronic stress and inflammation from lifelong exposure to discrimination. 研究人员分析了来自圣路易斯1,500多名成年人的17年数据,发现黑人参与者的死亡率为25%,白人参与者为12%,与压力有关的炎症占差异的49.3%。 Analyzing 17 years of data from over 1,500 St. Louis adults, researchers found Black participants had a 25% death rate versus 12% among White participants, with stress-related inflammation explaining 49.3% of the disparity. C-反应性蛋白和Interleukin-6(与长期压力相关联)等高位生物标志与早期死亡有关,支持“天候假设 ” 。 虽然研究强调系统性不平等是根本原因,但一半以上的差距仍然无法解释,这表明了其他因素,如获得医疗保健的机会和环境。 Elevated biomarkers like C-reactive protein and interleukin-6—tied to long-term stress—were associated with earlier death, supporting the “weathering hypothesis.” While the study highlights systemic inequities as a root cause, more than half the gap remains unexplained, pointing to additional factors like healthcare access and environment.