科学家发现了71个与狂躁症相连的双极紊乱基因,表明它引发了大部分遗传风险,与抑郁症不同。 Scientists found 71 genes tied to mania in bipolar disorder, revealing it drives most genetic risk and differs from depression.

研究人员利用来自600 000多人的数据,查明了71种基因变异物,这些变异物与两极疾病中的狂躁症具体相关。 Researchers have identified 71 genetic variants linked specifically to mania in bipolar disorder, using data from over 600,000 individuals. 研究发现狂躁症导致80%以上的病变, 与抑郁症不同, 与福利与教育的联系更紧密。 The study reveals mania drives over 80% of the disorder’s genetic variation and is distinct from depression, with stronger ties to wellbeing and education. 许多涉及基因的基因控制了脑细胞中的钙渠道,提出了新的治疗目标。 Many involved genes regulate calcium channels in brain cells, suggesting new treatment targets. 调查结果可提高诊断准确性,并导致个性化治疗。 The findings could improve diagnosis accuracy and lead to personalized therapies.