俄勒冈州研究人员创造了一种铁基纳米材料,利用有针对性的氧化压力摧毁小鼠的乳腺癌肿瘤,没有毒性,没有重复发生。 Oregon State researchers created an iron-based nanomaterial that destroys breast cancer tumors in mice using targeted oxidative stress, with no toxicity and no recurrence.

俄勒冈州立大学的研究人员开发了一种铁基纳米材料,通过生成两种活性氧物种 -- -- 氢氧基和单氧 -- -- 来杀死癌症细胞。 Researchers at Oregon State University have developed an iron-based nanomaterial that kills cancer cells by generating two reactive oxygen species—hydroxyl radicals and singlet oxygen—specifically within tumors. 纳米剂针对的是癌症细胞的酸性、高氢-过氧化环境,在保持健康组织的同时造成致命氧化压力。 The nanoagent targets the acidic, high-hydrogen-peroxide environment of cancer cells, causing lethal oxidative stress while sparing healthy tissue. 在人类乳腺癌的老鼠模型中,它导致肿瘤完全回归和长期的复发预防,没有系统毒性。 In mouse models of human breast cancer, it led to complete tumor regression and long-term recurrence prevention with no systemic toxicity. 与先前的治疗方法不同,这种双重行动方法显示了超高效力。 Unlike earlier treatments, this dual-action approach shows superior effectiveness. 该小组由联邦卫生研究所资助,计划对其他癌症(包括胰腺癌)进行测试。 The team, funded by federal health institutes, plans to test it against other cancers, including pancreatic cancer. 人类审判仍有待进行。 Human trials are still pending.