霍乱毒素使小鼠肿瘤生长减慢,针对癌症细胞,加强无副作用的免疫,为较安全的癌症治疗提供希望。 A cholera toxin slowed tumor growth in mice by targeting cancer cells and boosting immunity without side effects, offering hope for safer cancer treatments.

根据Umeå大学2025年的一项研究,一种霍乱衍生毒素 " Maka " 减缓了小鼠的直肠肿瘤生长,针对癌症细胞,在无损健康组织的情况下刺激免疫活动。 A cholera-derived toxin called MakA slowed colorectal tumor growth in mice by targeting cancer cells and boosting immune activity without harming healthy tissue, according to a 2025 study from Umeå University. 毒素在瘤中积累,增加癌细胞死亡, 通过增加巨细胞和中性粒细胞水平, 增强免疫反应. The toxin accumulated in tumors, increased cancer cell death, and enhanced immune responses by raising levels of macrophages and neutrophils. 它引发免疫信号,杀死癌症细胞,同时避免有害的炎症或器官损伤。 It triggered immune signals that kill cancer cells while avoiding harmful inflammation or organ damage. 在小鼠身上没有观察到任何副作用,即使在重复剂量的情况下也是如此。 No side effects were observed in mice, even with repeated doses. 研究人员说,Maka表示,作为有针对性的、毒性较低的癌症治疗,MakA有希望,但还需要进一步研究,以评估其在人类中的潜力。 Researchers say MakA shows promise as a targeted, less toxic cancer therapy, but further study is needed to assess its potential in humans.