一项水果苍蝇研究发现11种影响多巴胺和睡眠的人类基因,包括面具和Clu,为治疗帕金森氏病、抑郁症和睡眠紊乱提供了深刻见解。 A fruit fly study found 11 human genes affecting dopamine and sleep, including mask and clu, offering insights for treating Parkinson’s, depression, and sleep disorders.

利用果蝇进行的一项研究查明了11种与人类有关的基因,这些基因调节多巴胺水平和睡眠,产生两面和两面的强烈效果。 A study using fruit flies has identified 11 human-relevant genes that regulate dopamine levels and sleep, with two—mask and clu—showing strong effects. 研究人员筛选了与颜料相关的基因,这些基因与多巴胺有共同的路径,发现静默面罩减少了多巴胺,扰乱了睡眠模式,可与L-DOPA逆转,而Clu通过不同机制增加了睡眠。 Researchers screened genes linked to pigmentation, which shares pathways with dopamine, and found that silencing mask reduced dopamine and disrupted sleep patterns, reversible with L-DOPA, while clu increased sleep via a different mechanism. 研究结果可能会为帕金森氏病、抑郁症和睡眠障碍的治疗提供信息。 The findings may inform treatments for Parkinson’s, depression, and sleep disorders.