加拿大的一项研究开发了一项血液测试,通过将抗体点到细菌蛋白质上,在高危人群的症状出现之前2.5年,检测到克罗恩的疾病。
A Canadian study developed a blood test that detects Crohn’s disease up to 2.5 years before symptoms in high-risk individuals by spotting antibodies to a bacterial protein.
由加拿大牵头的一项研究发现,血检检测克罗恩的疾病,在症状开始两年半之前,先通过在遗传病易发个体中确定抗体为特定细菌蛋白质的抗体,从而检测出克罗恩的疾病。
A Canadian-led study has found a blood test that detects Crohn’s disease up to two-and-a-half years before symptoms start by identifying antibodies to a specific bacterial protein in genetically predisposed individuals.
该测试基于对Fangellin的免疫反应,在Crohn病人的5,000多名亲属中得到了验证,可能有助于早期干预或预防战略。
The test, based on immune responses to flagellin, was validated in over 5,000 relatives of Crohn’s patients and may help enable early intervention or prevention strategies.
研究结果发表在临床肠胃疾病学和肝病学中。
The findings were published in Clinical Gastroenterology and Hepatology.