瑞士的新方法追踪抗生素如何实时杀死个别细菌,显示抗生素比旧的试验更能预测治疗成功。 A new Swiss method tracks how antibiotics kill individual bacteria in real time, showing it better predicts treatment success than old tests.

巴塞尔大学研究人员开发的一种新方法 -- -- 抗微生物单细胞测试(ASCT) -- -- 使用高分辨率成像来跟踪抗生素在一段时间内如何杀死个别细菌,比传统的生长抑制测试更准确地衡量治疗效果。 A new method developed by University of Basel researchers, antimicrobial single-cell testing (ASCT), uses high-resolution imaging to track how antibiotics kill individual bacteria over time, offering a more accurate measure of treatment effectiveness than traditional growth inhibition tests. 在测试结核病和相关病原体后,该技术显示,实时杀戮,而不仅仅是抑制生长,可以更好地预测临床结果,并因菌株和遗传学的不同而有所不同。 Tested on tuberculosis and related pathogens, the technique revealed that real-time killing, not just growth suppression, better predicts clinical outcomes and varies by bacterial strain and genetics. 这种办法可导致个性化抗生素治疗和改进药物开发,尽管目前仍在研究使用。 The approach could lead to personalized antibiotic treatments and improved drug development, though it remains in research use for now.