全球50岁以下人群的结肠癌发病率正在上升，促使研究人员研究百年前的肿瘤样本以寻找病因。 Bowel cancer rates in people under 50 are rising worldwide, prompting researchers to study century-old tumor samples for causes.

全球50岁以下人群的结肠癌发病率正在上升，自1990年代以来增长了51%，这促使科学家们研究了英国圣马克医院保存的数万个肿瘤样本的独特档案。 Bowel cancer rates in people under 50 are rising globally, with a 51% increase since the 1990s, prompting scientists to study a unique archive of tens of thousands of preserved tumor samples from St Mark’s Hospital in the UK. 包括Kevin Monahan博士和Trevor Graham教授在内的研究人员正在利用现代分子技术分析这些世纪久的样本中的DNA损害模式,寻求与环境或生物因素的联系,如有害的肠道细菌、超处理食品、污染或抗生素。 Researchers, including Dr. Kevin Monahan and Prof. Trevor Graham, are using modern molecular techniques to analyze DNA damage patterns in these century-old samples, seeking links to environmental or biological factors like harmful gut bacteria, ultra-processed foods, pollution, or antibiotics. 目标是找出该疾病的早期发病原因,改进早期发现和预防战略。 The goal is to uncover causes behind the early onset of the disease and improve early detection and prevention strategies.