科学家发现了与高血压有关的脑电图区域,为与睡眠性脑膜高血压有关的高血压提供了新的治疗希望。
Scientists found a brainstem area linked to high blood pressure, offering new treatment hope for sleep apnea-related hypertension.
科学家已经确定脑电图中的横向辅助区域是高血压的主要驱动因素,将其与自动呼吸功能和血管收缩联系起来。
Scientists have identified the lateral parafacial region in the brainstem as a key driver of high blood pressure, linking it to automatic breathing functions and blood vessel constriction.
在动物模型中激活这个区域 降低血压 研究人员发现它受过度活性颈动体影响 颈部感应器 检测血氧水平 睡眠性脑膜中常见
Inactivating this area lowered blood pressure in animal models, and researchers found it's influenced by overactive carotid bodies—neck sensors that detect blood oxygen levels—common in sleep apnea.
针对这些传感器的重新用途药物可以提供一种更安全、间接的方式,减少血压而不跨越血脑屏障,有可能改善难以管理的高血压的治疗,特别是在与呼吸有关的疾病中。
A repurposed drug targeting these sensors may offer a safer, indirect way to reduce blood pressure without crossing the blood-brain barrier, potentially improving treatment for hard-to-manage hypertension, especially in breathing-related disorders.
这些研究结果发表在"循环研究"杂志上.
The findings were published in Circulation Research.