国民保健制度建议12个高危群体在对更年期或骨质疏松症使用tipolone之前先咨询医生。 The NHS advises 12 high-risk groups to consult a doctor before using tibolone for menopause or osteoporosis.

国民保健体系警告12个群体,在服用蛋白酮、治疗更年期症状的荷尔蒙疗法和预防骨质疏松症之前,应先咨询医生。 The NHS warns 12 groups should consult a doctor before taking tibolone, a hormone therapy for menopausal symptoms and osteoporosis prevention. 其中包括无法解释的阴道出血、败血症、内分泌高血肿、对乳房或雌激素敏感的癌症、血液凝块、凝血障碍、心脏病或中风史、肝病、稀有代谢紊乱或怀孕或哺乳的妇女。 These include women with unexplained vaginal bleeding, porphyria, endometrial hyperplasia, breast or estrogen-sensitive cancers, blood clots, clotting disorders, heart attack or stroke history, liver disease, rare metabolic disorders, or those who are pregnant or breastfeeding. 咨询意见强调在开始治疗之前先与保健提供者讨论风险。 The advice emphasizes discussing risks with a healthcare provider before starting treatment.