一项新的研究显示,个人化乳腺癌筛查减少了晚期病例,改进了只针对年龄以上人群的准则。 A new study shows personalized breast cancer screening reduces advanced cases and improves targeting over age-only guidelines.

对46 000名美国妇女进行的一项新研究发现,采用遗传、生物和生活方式因素进行个性化、基于风险的乳腺癌筛查比只按年龄进行的准则更为有效。 A new study of 46,000 U.S. women finds that personalized, risk-based breast cancer screening—using genetic, biological, and lifestyle factors—is more effective than age-only guidelines. 该研究在日本医学和医学协会中发表,表明这一方法减少了高级癌症病例,更好地针对高风险个人,避免了对低风险妇女的不必要的筛查。 Published in JAMA, the research shows this approach reduces advanced cancer cases, better targets high-risk individuals, and avoids unnecessary screenings for low-risk women. 值得注意的是,30%具有高风险基因变异的妇女没有家庭史,这意味着目前的准则可能会错过家庭史。 Notably, 30% of women with a high-risk genetic variant had no family history, meaning current guidelines may miss them. 专家们说,调查结果支持更新筛选标准,以便把个人风险评估置于基于年龄的规则之上。 Experts say the findings support updating screening standards to prioritize individual risk assessment over age-based rules.