印度科学家发现外胞蛋白对细胞清理至关重要，将其与阿尔茨海默病和癌症等疾病联系起来。 Indian scientists find exocyst proteins critical for cellular cleanup, linking them to diseases like Alzheimer’s and cancer.

JNCASR的印度科学家发现,八种Exocyst蛋白质中有七种对于酵母模型中的自发(细胞清理过程)至关重要。 Indian scientists at JNCASR have found that seven of eight exocyst proteins are crucial for autophagy, a cellular cleanup process, in yeast models. 该综合体以前与分泌相关联,对于形成清除受损部件的自发体至关重要。 The complex, previously linked to secretion, is essential for forming autophagosomes that remove damaged components. 当自噬被破坏时，会失败，导致与阿尔茨海默病、帕金森病和癌症相关的毒素积累。 When disrupted, autophagy fails, leading to toxic buildup tied to Alzheimer’s, Parkinson’s, and cancer. 这一发现揭示了外胞在细胞健康中的新作用，并通过靶向早期自噬体形成开辟了潜在的治疗途径。 The discovery reveals a new role for exocyst in cellular health and opens potential therapeutic avenues by targeting early autophagosome formation.