通过刺激肝细胞产生象胸腺一样的信号,一种新的MRNA疗法暂时恢复了老老鼠的免疫系统。 A new mRNA therapy temporarily rejuvenated aging mice's immune systems by stimulating liver cells to produce thymus-like signals.

2025年12月17日对自然的研究显示, 使用脂质纳米粒子进行两周一次的 mRNA疗法可以暂时恢复老老鼠的年轻免疫功能, 将肝细胞变成三个象胸腺一样的关键信号的工厂。 A December 17, 2025, study in Nature reveals that a twice-weekly mRNA therapy using lipid nanoparticles can temporarily restore youthful immune function in aging mice by turning liver cells into factories for three key thymus-like signals. 治疗促进了T细胞生产,改进了对疫苗和癌症免疫疗法的应对办法,为扭转与年龄有关的免疫衰减提供了一种安全的临时办法,而没有长期遗传变化。 The treatment boosted T-cell production and improved responses to vaccines and cancer immunotherapy, offering a safe, temporary approach to reversing age-related immune decline without long-term genetic changes.