新研究发现,与治疗的逐步递减对于阻止抗抑郁剂来说是最安全的。 Gradual tapering with therapy is safest for stopping antidepressants, new study finds.

《柳叶刀》精神病学的一项大型研究发现,根据对超过17 000名参与者的76项试验的分析,在获得心理支持的同时逐步消减抗抑郁药是终止药物治疗而不增加复发风险的最有效办法。 A large study in The Lancet Psychiatry finds that gradually tapering off antidepressants while receiving psychological support is the most effective way to discontinue medication without increasing relapse risk, based on an analysis of 76 trials with over 17,000 participants. 这种做法在防止复发方面与持续药物治疗一样有效,而且远远高于突然停药或迅速减缩。 This approach was as effective as continuing medication in preventing relapse and far superior to abrupt stopping or rapid tapering. 专家们强调需要更好地获得治疗和结构化支助,因为许多病人由于后续行动和获得精神保健的机会有限,在安全减少药物方面面临挑战。 Experts stress the need for better access to therapy and structured support, as many patients face challenges in safely reducing medication due to limited follow-up and mental health care access.