联合王国反对常规前列腺检查的建议,支持对具有BRCA基因的男子进行有针对性的检查。 UK advises against routine prostate screening, supports targeted testing for men with BRCA genes.

联合王国全国筛查委员会建议不为大多数男子进行常规前列腺癌筛查,理由是存在过度诊断的风险和假阳性的伤害,但支持每两年对具有BRCA1/2型基因突变的男子进行有针对性的筛查,从45岁开始,每两年进行一次。 The UK National Screening Committee recommends against routine prostate cancer screening for most men, citing risks of overdiagnosis and harm from false positives, but supports targeted screening every two years for men with BRCA1/2 gene mutations starting at age 45. 该决定依据的证据表明,目前采用的方法缺乏足够的利益来大于伤害,因此排除了黑人男子和那些由于数据不足而具有家庭历史的人。 The decision, based on evidence that current methods lack sufficient benefit to outweigh harms, excludes Black men and those with family histories due to insufficient data. 目前正在进行为期12周的公众协商,预计将于2026年3月提出最后指导。 A 12-week public consultation is underway, with final guidance expected in March 2026. 该委员会正在等待4 200万英镑的FORFORM试验综合方法的结果,包括基因测试和MRI扫描,以改进检测。 The committee awaits results from the £42 million TRANSFORM trial testing combined approaches including genetic testing and MRI scans to improve detection.