临床试验发现,在1型糖尿病患者中,美丙胺在不增加胰岛素抗药性的情况下,将胰岛素需求减少了12%。 A clinical trial found metformin reduces insulin needs by 12% in type 1 diabetes patients without improving insulin resistance.

澳大利亚一项新的临床试验发现,Medformin是一种常见的糖尿病药物,它在1型糖尿病患者中将胰岛素需求减少了约12%,尽管没有改善胰岛素的抗药性。 A new Australian clinical trial found that metformin, a common diabetes drug, reduces insulin needs by about 12% in people with type 1 diabetes, despite not improving insulin resistance. 为期六个月的研究涉及40名患有长期1型糖尿病的成人,使用了精确的代谢测试,发现胰岛素敏感度没有重大变化,但胰岛素剂量明显减少。 The six-month study, involving 40 adults with long-term type 1 diabetes, used precise metabolic testing and found no significant change in insulin sensitivity, but a meaningful decrease in insulin dosage. 研究人员说,这可以减轻日常使用胰岛素的生理和情感负担,为治疗提供潜在的低成本补充。 Researchers say this could ease the physical and emotional burden of daily insulin use, offering a potential low-cost addition to treatment. 发表在《自然通讯》上的这些发现表明，二甲双胍可能有助于改善生活质量，尽管仍需进一步研究以了解其机制。 The findings, published in Nature Communications, suggest metformin may help improve quality of life, though further research is needed to understand the mechanism.