山山西奈研究人员通过修复淋巴功能障碍、改善血细胞生产,扭转了老鼠血干细胞的老化趋势。 Mount Sinai researchers reversed aging in mouse blood stem cells by fixing lysosomal dysfunction, improving blood cell production.

西奈山的研究人员通过修复细胞衰老的主要驱动因素,即淋巴瘤功能障碍,扭转了小鼠血液成型干细胞的老化趋势。 Researchers at Mount Sinai have reversed aging in blood-forming stem cells in mice by fixing lysosomal dysfunction, a key driver of cellular aging. 通过遗传或药物方法恢复淋巴功能,提高了细胞生产健康血细胞的能力,为治疗与年龄有关的血液紊乱和增强老年人的免疫力提供了可能的战略。 Restoring lysosomal function through genetic or drug-based methods improved the cells' ability to produce healthy blood cells, offering a potential strategy to treat age-related blood disorders and boost immunity in older adults. 这些研究结果公布在细胞针尖细胞中,目前仅限于小鼠,但表明今后针对细胞老化的人类治疗有希望的途径。 The findings, published in Cell Stem Cell, are currently limited to mice but suggest promising pathways for future human therapies targeting cellular aging.