阻止EYA和PLK1蛋白质在实验室研究中杀死抗药性强的癌症。
Blocking EYA and PLK1 proteins kills aggressive, resistant cancers in lab studies.
澳大利亚研究人员发现,堵塞两种蛋白质,即EYA和PLK1,同时通过合成致命效果杀死抗治疗性癌症,如神经细胞瘤和血浆瘤。
Australian researchers have found that blocking two proteins, EYA and PLK1, simultaneously kills aggressive, treatment-resistant cancers like neuroblastoma and glioblastoma through a synthetic lethal effect.
该研究发表在Genes & Development上。 研究显示,癌症细胞依靠两种蛋白质生存,使两者的结合抑制成为有希望的新疗法途径。
The study, published in Genes & Development, shows cancer cells depend on both proteins to survive, making their combined inhibition a promising new therapy path.
这一发现可能导致对难以治疗的肿瘤进行定向治疗。
The discovery could lead to targeted treatments for hard-to-treat tumors.