2025年5月,医生利用CRISPR治疗患有罕见遗传障碍的儿童,这标志着个性化医学的一大进步。 In May 2025, doctors used CRISPR to treat a child with a rare genetic disorder, marking a major advance in personalized medicine.

2025年5月,费城儿童医院的医生使用CRISPR基因编辑来治疗患有罕见遗传障碍的儿童,这标志着个性化医学的一大进步。 In May 2025, doctors at Children’s Hospital of Philadelphia used CRISPR gene editing to treat a child with a rare genetic disorder, marking a major advance in personalized medicine. 该技术由细菌防御系统产生,于2012年开发,到2023年使200多次实验治疗得以进行,到2025年年中在多个国家导致对像Vertex的CASGEVY这样的CRISPR疗法的监管核准。 The technology, derived from a bacterial defense system and developed in 2012, has enabled over 200 experimental treatments by 2023 and led to regulatory approvals for CRISPR therapies like Vertex’s CASGEVY in multiple countries by mid-2025. 现在的创新包括基础和初级编辑、后继基因改造和CRISPR强化的乙型移植,猪肾被成功地移植到人体内。 Innovations now include base and prime editing, epigenetic modifications, and CRISPR-enhanced xenotransplantation, with pig kidneys successfully transplanted into humans. 尽管取得了迅速进展,但伦理问题和安全风险依然存在,特别是来自无管制的DIY生物黑客。 Despite rapid progress, ethical concerns and safety risks persist, particularly from unregulated DIY biohacking.