研究人员指出,慢性应激伤害小鼠脑细胞,减少血液流动,提高阿尔茨海默氏病的风险。 Chronic stress harms brain cells in mice, reducing blood flow and raising Alzheimer’s risk, researchers say.

在2025年11月11日发表的《电子生活》中,本州的一项研究发现,慢性压力会损害小鼠的1型NNOS神经元,导致大脑血液流动减少,神经活动减弱,特别是在睡眠期间。 A Penn State study published November 11, 2025, in eLife finds that chronic stress can damage type-one nNOS neurons in mice, leading to reduced brain blood flow and weakened neural activity, especially during sleep. 这些稀有的神经元 有助于调节血管的振荡 这对于输送氧气和营养物至关重要 These rare neurons help regulate blood vessel oscillations critical for delivering oxygen and nutrients. 其因压力引起的损失会扰乱大脑沟通,并可能增加阿尔茨海默氏等神经退化性疾病的风险。 Their loss, triggered by stress, disrupts brain communication and may increase the risk of neurodegenerative diseases like Alzheimer’s. 尽管在小鼠体内进行,但研究人员认为,由于类似的大脑结构,研究结果很可能适用于人类。 Though conducted in mice, researchers believe the findings likely apply to humans due to similar brain structures. 这项研究由NIH和美国心脏协会资助,并计划在今后开展研究,探讨与痴呆症遗传风险的联系。 The study was funded by the NIH and American Heart Association, with future research planned to explore links to genetic risks for dementia.