在一项小型研究中,将三种心脏衰竭药物结合起来的多孔虫改善了心脏功能,减少了住院人数。 A polypill combining three heart failure drugs improved heart function and reduced hospitalizations in a small study.

在美国心脏协会 2025 年科学会议上发表的一项新研究发现，每天一次的复方药丸结合了三种心力衰竭药物——琥珀酸美托洛尔、螺内酯和恩格列净——可改善心脏功能，减少住院率，提高服药依从性，并提高患有心力衰竭和射血分数降低的成年人的生活质量。 A new study presented at the American Heart Association’s 2025 Scientific Sessions found that a once-daily polypill combining three heart failure drugs—metoprolol succinate, spironolactone, and empagliflozin—improved heart function, reduced hospitalizations, boosted medication adherence, and enhanced quality of life in adults with heart failure and reduced ejection fraction. 在212名参与者中,多药丸组的排泄分数增加了3.4%,心力衰竭相关住院病例减少了60%,药物检测率高于标准治疗. Among 212 participants, the polypill group saw a 3.4% increase in ejection fraction, a 60% drop in heart failure-related hospitalizations, and higher drug detection rates compared to standard care. 初步的和尚未经过同侪审查的调查结果表明,简化治疗可能有助于克服这个复杂的病人人口中的坚持治疗方面的挑战。 The findings, preliminary and not yet peer-reviewed, suggest simplified treatment may help overcome adherence challenges in this complex patient population.