产前COVID-19接触与儿童,特别是男孩和第三季度感染儿童神经发育紊乱风险较高有关联。 Prenatal COVID-19 exposure linked to higher neurodevelopmental disorder risk in children, especially boys and third-trimester infections.

从2020年3月至2021年5月,马萨诸塞州对18 000多名新生儿进行了一项大型研究,结果发现,在子宫内感染COVID-19的儿童,如三岁前出现言语或运动迟发等神经发育紊乱的几率要高29%,男孩的风险最高,在第三个三个月感染时风险最高。 A large Massachusetts study of over 18,000 births from March 2020 to May 2021 found that children exposed to COVID-19 in the womb had a 29% higher odds of neurodevelopmental disorders like speech or motor delays by age three, with the highest risk in boys and when infection occurred in the third trimester. 大多数母亲未接种疫苗,该研究利用普遍检测来查明感染。 Most mothers were unvaccinated, and the study used universal testing to identify infections. 虽然总体风险仍然很低,但研究人员认为,严重感染导致产妇发炎可能会破坏胎儿大脑发育,特别是在第三个季度大脑迅速成长期间。 While the overall risk remains low, researchers suggest maternal inflammation from severe infection may disrupt fetal brain development, particularly during rapid brain growth in the third trimester. 该研究没有证明因果关系,专家们指出,由于豁免和变式,目前的风险可能较低。 The study does not prove causation, and experts note that current risks may be lower due to immunity and variants.