侵入血管的肿瘤可能会通过凝固, 而不是通过增长, 导致癌症死亡。 新的研究发现。
Tumors invading blood vessels may cause cancer deaths via clotting, not just growth, new study finds.
一项新的研究表明,癌症可能杀死的病人并非仅仅是肿瘤生长造成的,而是肿瘤侵入主要血管时引发的血凝块造成的。
A new study suggests cancer may kill patients not from tumor growth alone, but through blood clots triggered when tumors invade major blood vessels.
研究人员分析了100多名结肠、肺、卵巢、肝或胰腺癌患者的解剖和医疗数据,发现肿瘤经常渗入接近死亡的大型血管。
Researchers analyzed autopsies and medical data from over 100 patients with advanced colon, lung, ovarian, liver, or pancreatic cancer, finding tumors frequently infiltrated large vessels near death.
血液检测显示,循环癌细胞呈上升趋势,对1 250名德国病人的CT扫描证实,船只参与情况很普遍。
Blood tests showed a spike in circulating cancer cells, and CT scans of 1,250 German patients confirmed widespread vessel involvement.
团队的理论认为,血流中的肿瘤碎片会助长凝结,限制血液流向重要器官,并导致器官衰竭。
The team theorizes that tumor fragments in the bloodstream promote clotting, restricting blood flow to vital organs and causing organ failure.
这或许可以解释尽管癌症流行,但突然死亡的原因。
This may explain sudden deaths despite widespread cancer.
计划进行临床试验,以测试诸如手术或针对肿瘤-船只接触的辐射等治疗是否能够延长存活期,从而有可能改变对先进的癌症的管理方式。
A clinical trial is planned to test whether treatments like surgery or radiation targeting tumor-vessel contact can extend survival, potentially changing how advanced cancer is managed.