如果胎盘生长因子水平在20至24周之间低于832 pg/ ml,那么患有状细胞病的孕妇患早发性子宫的风险更高. Pregnant women with sickle cell disease are at higher risk for early-onset preeclampsia if placental growth factor levels are below 832 pg/mL between 20 and 24 weeks.

患有镰状细胞疾病的孕妇面临早发先兆子痫的较高风险,这种危险状况与高血压和器官损伤有关。 Pregnant women with sickle cell disease face a higher risk of early-onset preeclampsia, a dangerous condition linked to high blood pressure and organ damage. 一项新的研究发现,低水平的胎盘生长因子 (PlGF),特别是在20至24周之间低于832 pg/ ml,强烈预测这些患者的早期妊娠前,尽管他们的自然增加的PlGF水平. A new study finds that low levels of placental growth factor (PlGF), particularly below 832 pg/mL between 20 and 24 weeks, strongly predict early-onset preeclampsia in these patients, despite their naturally elevated baseline PlGF levels. 该研究以83名患有镰状细胞病的妇女为基础,显示低位PlGF与胎盘血液流动不良和胎儿生长问题相关。 The research, based on 83 women with sickle cell disease, shows low PlGF correlates with poor placental blood flow and fetal growth issues. 调查结果虽然仅限于一个中心,但支持利用PlGF测试查明高危怀孕情况并指导早期干预。 While limited to one center, the findings support using PlGF testing to identify at-risk pregnancies and guide early interventions. 目前正在进行一项国际研究,以验证用于改善产前护理的风险计算器。 An international study is underway to validate a risk calculator for improved prenatal care.