狗血检表明,与肾功能有关的生物标志已经老化,有可能进行人类抗菌研究。
Dog blood tests reveal aging biomarkers linked to kidney function, with potential for human anti-aging research.
根据一项涉及狗老化项目近800只狗的研究,狗的血检可能有助于揭示人类老化的关键真知灼见。
Blood tests in dogs may help reveal key insights into human aging, according to a study involving nearly 800 dogs from the Dog Aging Project.
研究人员发现,狗血中的小分子超过40%,包括经翻译后改变的氨基酸,与蛋白质分解有关,随着年龄变化,可能反映肾功能下降。
Researchers found that over 40% of small molecules in dog blood, including post-translationally modified amino acids linked to protein breakdown, change with age and may reflect declining kidney function.
这些代谢物受直肠细菌和遗传学影响,可以作为加速老龄化和健康下降的生物标志。
These metabolites, influenced by gut bacteria and genetics, could serve as biomarkers for aging pace and health decline.
调查结果基于不同品种和大小的狗提供的数据,表明在跟踪生物老化和测试抗老化治疗方法方面的潜在应用,可能对这两种物种都有好处。
The findings, based on data from dogs of various breeds and sizes, suggest potential applications in tracking biological aging and testing anti-aging treatments, with possible benefits for both species.
这项研究由国家卫生研究所和其他团体资助,目前正在进行中,计划监测随时间推移发生的变化,并探讨与肌肉丧失和寿命延长的联系。
The study, funded by the NIH and other groups, is ongoing, with plans to monitor changes over time and explore links to muscle loss and longevity.