CRISPR编辑的猪抵制致命猪热, CRISPR-edited pigs resist deadly swine fever, offering safer, more sustainable farming.

利用CRISPR技术开发了抗古典猪热的基因编辑猪,改变DNAJC14蛋白,以阻止病毒复制。 Gene-edited pigs resistant to classical swine fever have been developed using CRISPR technology, altering the DNAJC14 protein to block viral replication. 经过编辑的猪在英国动物和植物卫生署测试后发现,接触后没有任何疾病或病毒存在,这不同于未经编辑的控制措施。 Tested at the UK’s Animal and Plant Health Agency, the edited pigs showed no illness or virus presence after exposure, unlike unedited controls. 这一突破由爱丁堡大学的Roslin研究所领导,可以减少大规模烹饪、改善动物福利和降低农业成本。 The breakthrough, led by the University of Edinburgh’s Roslin Institute, could reduce mass culling, improve animal welfare, and lower farming costs. 同样的修改也可保护牛和羊免受相关病毒的侵害。 The same modification may protect cattle and sheep from related viruses. 英格兰正在等待基因编辑牲畜的监管批准,但类似的动物在美国、日本和巴西已经获得批准。 Regulatory approval for gene-edited livestock is pending in England, though similar animals are already approved in the U.S., Japan, and Brazil. 在多代人中没有观察到任何不利影响,该技术正在考虑用于商业用途。 No adverse effects have been observed in multiple generations, and the technology is being considered for commercial use.